miRNA and Epigenetics
miRNA and Epigenetics
Doug Brutlag
Lecture Materials
miRNA Regulatory Network Slides
Epigenetics Slides
Lecture Video
An Epigenetics Primer
Epigenetics Marks Regulatory Elements
An Epigenetic inheritance
Epigenetics Suicide Note
Epigenetic Changes in Cancer
NOVA Show on Epigenetics
A Tale of Two Mice
Epigenetics expert Q&A
RNAi
Personal Genome Project
Epigenetics for Teachers
miRNA Literature References
•Role of miRNAs in Cancer and Apoptosis Lynan-Lennon Biol Rev Camb Philos Soc. 2009 Feb;84(1):55-71
•Causes and consequences of microRNA dysregulation in cancer Croce Nat Rev Genet. 2009 Oct;10(10):704-14.
•miRNAs as oncogenes and tumor suppressors. Zhang Dev Biol. 2007 Feb 1;302(1):1-1
•Transcriptional regulatory networks in Saccharomyces cerevisiae. Lee Science. 2002 Oct 25;298(5594):799-804.
•RNA regulation: a new genetics? Mattick Nat Rev Genet. 2004 Apr;5(4):316-23.
•microRNA functions. BushatiAnnu Rev Cell Dev Biol. 2007;23:175-205.
•Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?Filiowicz Nat Rev Genet. 2008 Feb;9(2):102-14.
•Post-transcriptional gene silencing by siRNAs and miRNAs. Filipowicz Curr Opin Struct Biol. 2005 Jun;15(3):331-41.
•The microRNAs of Caenorhabditis elegans. Lim Genes Dev. 2003 Apr 15;17(8):991-1008.
•A three-dimensional view of the molecular machinery of RNA interference. Jinek Nature. 2009 Jan 22;457(7228):405-12.
•miRNAs and Cancer AAAI Science Webinars February 20 with George Calin, Brank Slack and Scott Hammond
•Short RNAs repress translation after initiation in mammalian cells. Petersen Mol Cell. 2006 Feb 17;21(4):533-42.
•Raising the estimate of functional human sequence. Pheasant Genome Res. 2007 Sep;17(9):1245-53.
•A developmental view of microRNA function. Zhao Trends Biochem Sci. 2007 Apr;32(4):189-97.
•c-Myc-regulated microRNAs modulate E2F1 expression O’Donnnell Nature. 2005 Jun 9;435(7043):839-43.